Here's my first-impressions review:
http://www.penultimateharn.com/blog/?p=115.
In a nutshell, I'm impressed with what I've read so far, but I only got my copy yesterday. I don't mind admitting that I stayed up all night reading the rules and making my first character (which I messed up).
I want some more time with it before I really make up my mind, but everything I'm seeing so far indicates that this will probably become my favourite iteration of Traveller (which I'm glad about as I've always been torn between MT and GT).
Plus points in brief
1) Very definitely Traveller.
2) Looks incredibly flexible. Not Hero System flexible, but flexible in the SF genre.
3) Very legible, functional layout
4) Some very innovative, interesting ideas
5) Lots of snippets of colourful Imperium background.
6) I was a little suspicious when I heard about the dice pool mechanics, but having tried them, I think they work very well indeed. Tasks have never been so simple to implement.
7) Updates Traveller's tech without losing Traveller's feel. Genetic engineering, bits of cyberwear, cyborgs.
8) The makers. Farily simple, and sufficiently flexible. Gunmaker, armormaker, vheiclemaker, sophontmaker, thingmaker...
Cons in brief
1) No index. It could really use one. Hopefully either Marc or the fan community can create a PDF one eventually.
2) Organisational oddities - rules on exotic worlds come in the benchmark chapter, near the front, not in the worlds chapter, for instance.
3) Not always clear on fine details - or maybe I just can't find some because of the lack of an index. How many times can you change career? There's mention of Career Change Options, but I can't find the rules on them.