The smallest nuclear pumped x-ray detination laser warhead in TNE is the 10kilotonne.
Assuming this equates to 10,000kilos of TNT this equates to 60,000DP, which results in a concussion/penetration of 866. Doubled if "Tamped" and halved if not. Reading TNE's description of "Tamping" I'd say it would be unlikely to get a tamped charge against a starship hull and I wouldn't consider a hull hit from a Nuclear Det laser warhead missile to be considered tamped either as they're not designed to actually "hit" hulls.
Thus we get a penetration of 433. Divide that figure by the toughness of your targets hull material (in TNE superdense is 14/cm) and you get 30.9. Subtract the thickness in cm and you arrive at the diameter of the hole the explosion made. So if that 10k-20k cruiser had 10cm thick hull armour (which would be AV:140 and perhaps a tad light) you've put a 20.9cm diameter hole in the vessel. Interpret that how you will.
However, if you took your penetration 433 result straight to the damage cards for Brilliant Lances you would have to go to the very end of the critical hits table (the 201+ column) and see that in addition to scoring the maximum 5 major damage results in the one location, 101-120 points, plus 15 major damage results in adjacent locations(433points), you've also scored atleast 4 critical hits on a large (10,000kt+) target.
You've also got a chance to have simply vapourized the target as inflicting any critical hits gives you this chance. Roll number of critical hits or less on a d20. 201+ column says 4 for a large target but remember we've done 433 so you'd be within rights to say 8 critical hits if you chose. 8 or less on a d20 is destinctly possible hmmmmn? And that is the smallest nuke det warhead! No wonder they shyed away from having missile hull hits in TNE.