1. The Ancients as presented in cannon have a number of serious problems... starting with the time-line.
They supposedly spread humanity around the galaxy about 300,000 years ago... and most of those sub-species are still supposed to be interfertile.
Any geneticist will tell you that is BS... there have been so many changes in the sol genotype in that time that there is no way we could interbreed with our ancestors... much less with others who also have 300,000 years of divergent genetic drift/mutation in entirely different environments.
The only way that would work is for the spreading to have occurred in the more recent past... more like 70,000 - 30,000 years ago... and most likely the smaller number.
A quick reference may be found here:
http://www.pbs.org/wgbh/evolution/humans/humankind/m.html
Note that only Homo erectus and Homo heidelbergensis were around in the canon period... and man has evolved considerably since that period.
Of course, there could have been "genetic guidance" from surviving Ancients... yeah, right!
In my Universe, Yaskodaddy is basically a myth... there was a genetic change in the Droyne that led to the Chirper mutation and the fall of their civilization, and the Coyns were developed by an outside civilization & species to restore the functionality of Chirper/Droyne cerebral processes.
There have been many "Ancient" [I use Andre Norton's term "Forerunner"] civilizations and species throughout Galactic history... some overlapping, and some in isolation.
These have occurred as recently as a few (single digit) thousand years before the development of the jump drive by the Vilani in ~2,000 BC sol dating.
There are lots of Forerunner artifacts to be found... from many different civilizations, but extremely few of them are in good enough shape to aid in the development of new technology... and even fewer have any chance of working.
Their main value is to science and collectors, and either route can be profitable to the PCs.
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