I've been working on a GURPS Space 4e system generator Excel utility for quite some time. It generates the physical data OK, but I need to add settlement info (population, tech level, government, etc.) and create a good format for the final output.
I've wanted a way to generate a sector where each world has a chance to influence the development of other worlds. I'd like a way to propagate major worlds, colonies and outposts throughout a sector, based on regional powers, randomized (but logical) events and influences. For example, a high-population, technologically advanced garden world would tend to increase the likelihood and extent of development on other worlds nearby; a major conflict or disaster on a major world could affect trade, refugee migrations and political unrest on nearby worlds.
This being said, I have little time for this sort of thing these days. It may remain no more than a thought-experiment until I retire or win the lottery.